Dr. Matthew Johnson: Psychedelics for Treating Mental Disorders | Huberman Lab Podcast #38

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This episode I discuss medical research on psychedelic compounds with Dr. Matthew Johnson, Professor of Psychiatry and Behavioral Sciences at Johns Hopkins School of Medicine. We discuss the biology of MDMA, LSD, psilocybin and ayahuasca. Dr. Johnson shares the results of clinical trials in his laboratory that reveal the potential of these compounds for treating depression, addiction, eating disorders, ADHD and other mental disorders. Dr. Johnson explains how he conducts a typical psychedelic experiment at his lab, from start to finish. He also outlines the conditions necessary for optimal clinical results. He also explains the dangers, common myths, and pitfalls of psychedelic medicine. Dr. Johnson discusses flashbacks, the increased risks for certain age groups and people using psychedelics, and the constantly changing legal and pharmaceutical industry landscape around psychedelics. Dr. Johnson also discusses how scientific research on psychedelics will determine the future direction of psychiatric medicine. Johnson is one of a few researchers who pioneered clinical research on these powerful compounds. Johnson has unparalleled insight into the ways these compounds can be integrated into other psychiatric treatments. This allows for a change in one’s perception of self and reality.

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Links:
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Chris Letheby’s upcoming book

Timestamps:
00: 00: 00 Introducing Dr. Matthew Johnson
00: 02: 10 Supporting Sponsors
00: 06: 40 ‘Psychedelics’ Defined
00: 14: 09 Hallucinations, Synesthesia, Altered Space-Time Perception
00: 19: 56 Serotonin & Dopamine
00: 23: 50 Ketamine & Glutamate
00: 28: 00 An Example Psychedelic Experiment
00: 37: 30 ‘Letting Go’ with Psychedelics
00: 44: 10 Our Mind’s Eye
00: 48: 00 Redefining Your Sense of Self
00: 58: 56 Exporting Psychedelic Learnings to Daily Life
01: 04: 36 Flashbacks
01: 12: 10 Ayahuasca, & ASMR, Kundalini Breathing
01: 15: 54 MDMA, DMT
01: 26: 00 Dangers of Psychedelics, Bad Trips, Long-Lasting Psychosis
01: 38: 15 Micro-Dosing
01: 56: 45 Risks for Kids, Adolescents & Teenagers; Future Clinical Trials
02: 03: 40 Legal Status: Decriminalization vs. Legalization vs. Regulation
02: 18: 35 Psychedelics for Treating Concussion & Traumatic Brain Injury
02: 27: 45 Shifting Trends in Psychedelic Research, Academic Culture
02: 44: 23 Participating in a Clinical Trial, Online Survey Studies, Breathwork
02: 50: 38 Conclusions, Subscribing & Supporting the HLP, Supplements

The Huberman Lab Podcast does not include Dr. Huberman’s research and teaching roles at Stanford University School of Medicine. This podcast is not intended to replace medical advice. The Huberman Lab Podcast, its guests, and affiliates, assume no responsibility for the use of the information.

Photo credit for Title Card: Mike Blabac – m

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